-Lipotropin is a hormone produced by the cleavage of pro-opiomelanocortin (POMC). The anterior pituitary gland produces the pro-hormone POMC, which undergoes cleavage to adrenocorticotropin (ACTH) and β-lipotropin (β-LPH) which is a 90 amino acid polypeptide that is the carboxy-terminal fragment of POMC. It is the predominant opioid peptide of the human pituitary and rat pars distalis and is present in concentrations essentially equimolar with corticotropin.
-It stimulates melanocytes to produce melanin, and can also be cleaved into smaller peptides. In humans, γ-lipotropin, α-MSH, β-MSH, γ-MSH, α-endorphin, ß-endorphin, γ-endorphin, and met-enkephalin are all possible fragments of beta-lipotropin. Beta-lipotropin also performs lipid-mobilizing functions such as lipolysis and steroidogenesis.
Target: beta Lipotropin
Host: Rabbit (Rb)
Application: Immunohistochemistry (IHC)
Product Type: Polyclonal Antiserum
Species Reactivity: Human (H), Mouse (M), Rat (R)
Format: Whole Serum - liquid
Volumne: 50 ul
Immunogen: N-terminal portion of bovine beta-Lipotropin conjugated to thyroglobulin
Antibody Type: Polyclonal