-Endomorphins are recently discovered endogenous opioid peptides composed of four amino acids: Endomorphin-1 (EM-1) is Tyr-Pro-Trp-Phe-NH2, and Endomorphin-2 (EM-2) is Tyr-Pro-Phe-Phe-NH2. These peptides have a very high affinity and specificity for mu-opioid receptors as it has been reported in many pharmacological studies.

-EM-1 is distributed in many brain regions, whereas EM-2 is prevalent in brainstem and spinal cord. EM-1 and EM-2 exert their antinociceptive activity by interacting with mu-opioid receptors. EM-1 anf EM-2 bind with mu-opioid receptor with high affinity and selectivity in comparison with binding to opioid delta and kappa receptors. EM-1 and EM-2 tetrapeptides activate G-proteins and inhibit adenylyl cyclase activity when bind to mu-opioid receptors.       

 

Specification:

Target: Endomorphin 1&2

Host: Rabbit (Rb)

Application: Immunohistochemistry (IHC)

Product Type: AFP

Species Reactivity: Human (H), Mouse (M), Rat (R), Primate (Pr)

Format: Affinity Purified - Liquid          

Volumne: 50 ul

Immunogen Details: None Reported

                                               

Label: Unlabeled

Antibody Type: Polyclonal

 

      

 

    

Endomorphin 1&2

SKU: 61-351
Size
Host
Application
Species Reactivity
Manufacture
  • 추가문의사항은 info@imedico.co.kr 로 연락주세요.

MEDICO   

Tel : 070-8615-5557  Fax : 0504-981-5578

  • Facebook Social Icon
  • Twitter Social Icon
  • Google+ Social Icon

​Job openings   |   개인정보취급방침    |   Investment

3 대_300x.png

COPYRIGHT© 2016 by Medico. All rights reserved.