-Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8.
-mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
Host: Rabbit (Rb)
Application: Immunoblot (IB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)
Product Type: Whole Serum
Species Reactivity: Mouse (M), Rat (R)
Format: Sent in liquid form in tris Glycine with 0.1% sodium azide and 1% BSA, pH 7.8
Volumne: 100 ul
Immunogen: NGREVVDSTTSSLmGIuR3 Corresponding to the carboxy-terminus of rat mGLuR2
Antibody Type: Polyclonal