-Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8.
-mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells. mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.
Host: Rabbit (Rb)
Application: Immunoblot (IB)
Product Type: AFP
Species Reactivity: Mouse (M), Rat (R)
Format: Affinity purified. Sent in liquid form in Tris Glycine with 0.1% sodium azide and 1% BSA.
Volumne: 100 ul
Antibody Type: Polyclonal