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-Metabotropic glutamate receptors (mGluRs) are G-protein coupled receptors activated by glutamate. Based on sequence similarity, transduction mechanisms and agonist potencies, mGluRs are subdivided into three groups: mGluR1/mGluR5, mGluR2/mGluR3, and mGluR4/mGluR6/mGluR7/mGluR8. mGluRs are widely distributed throughout the nervous system and are expressed by both neurons and glial cells.

-mGluRs have been suggested to play a variety of functional roles, among which is involvement in synaptic plasticity underlying learning and memory as well as chronic pain.

 

Specification:

Target: mGluR6

Host: Rabbit (Rb)

Application: Immunoblot (IB), Immunocytochemistry (ICC), Immunohistochemistry (IHC)

Product Type: AFP

Species Reactivity: Mouse (M), Rat (R)

Format: Liquid. 0.1% BSA, Tris-glycine with 0.1% Sodium Azide. Concentration 1mg/mL

Volumne: 100 ul

Immunogen: AAPQNENAEDAK Corresponding to the carboxy- terminus of rat mGIuR6                                                                                        

Label: Unlabeled

Antibody Type: Polyclonal

 

      

 

    

mGluR6

SKU: 61-181
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