-"PGP9.5 is a soluble cytoplasmic protein with a molecular weight of approximately 25,000 kD. It is present in neurons and in cells of the diffuse neuroendocrine system. PGP9.5 functions as a tissue-specific ubiquitin carboxyl terminal hydrolase isoenzyme. This enzyme is also known as UCH-L1. Because of its abundance in nerves, it has been widely used as a marker for peripheral nerve fibers

-It was also discovered as a gene mutated in some rare famial forms of Parkinson's disease. Interestingly a common allelic variant of UCHL1, the S18Y polymorphism is actually protective against Parkinson's disease. It is also a marker for cells of the diffuse neuroendocrine system and their tumors "

 

Specification:

Target: PGP9.5 [175-191]

Host: Guinea Pig (GP)

Application: Immunohistochemistry (IHC)

Product Type: Polyclonal Antiserum

Species Reactivity: Human (H), Mouse (M), Rat (R)

Format: Whole Serum (with 0.05% sodium azide) Sent in liquid form

Volumne: 50 ul & 150 ul

Immunogen Details: GASSEDTLLKDAAKVCR

                                Corresponding to residues 175-191 of soluble cytoplasmic protein

                                human PGP9.5                                

Label: Unlabeled

Antibody Type: Polyclonal

 

      

 

    

PGP9.5 [175-191]

SKU: 61-402
Size
Host
Application
Species Reactivity
Manufacture
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